I admit it: I'm too easily excited and tend to install about any kind of Beta that I get my hands on on my machines. That's how the WUS trial found its way on the domain controller, and aside from the disk space requirements that initially bit me, it is smooth sailing so far. Of course, I didn't put all machines "on the line":

Doing it via AD and a group policy also enables you to set the various options rather easily from one single central location:

What's that got to do with .NET development? Easy: I have tons of VPC images, and it is rather too easy (and dangerous) to forget to patch one of those. Now everything is taken care of automatically without wasting Internet bandwidth.